Strychnos nux-vomica L. seed preparation promotes functional recovery and attenuates oxidative stress in a mouse model of sciatic nerve crush injury
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چکیده
منابع مشابه
Crocin Enhanced Functional Recovery after Sciatic Nerve Crush Injury in Rats
Objective(s): Crocin is a constituent of saffron and has many biological functions. The present study aimed to investigate the effects of intraperitoneal (IP) injection of crocin on sciatic nerve regeneration in male Wistar rats. Materials and Methods: Fifty-four rats were divided into 9 groups: groups 1-4 (intact + normal saline and intact + crocin at doses of 5, 20 and 80 mg/kg, respectively)...
متن کاملA short review on anticancer investigations of Strychnos nux-vomica
Herbs used in traditional medicine have provided a nidus for the discovery of various new molecules having therapeutic viability. With the advent of various diseases, the science has also armed itself to combat the everevolving family of diseases with the help of these new molecules. Cancer is one such area which has limited scope for management through conventional therapy. Recent research adv...
متن کاملCurcumin promotes nerve regeneration and functional recovery in rat model of nerve crush injury.
BACKGROUND AND AIM Curcumin at 100mg/kg has been shown to have a protective effect on crush nerve injury. However, it is unclear whether the protective effect of curcumin on nerve injury is dose dependent. The present study was designed to investigate such a possibility. METHODS The rats subjected to crush nerve injury were intraperitoneally administrated daily for 4 weeks with curcumin (50 m...
متن کاملStrychnos nux-vomica seeds: Pharmacognostical standardization, extraction, and antidiabetic activity
BACKGROUND Strychnos nux-vomica, commonly known as kuchla, contains strychnine and brucine as main constituents. Minor alkaloids present in the seeds are protostrychnine, vomicine, n-oxystrychnine, pseudostrychnine, isostrychnine, chlorogenic acid, and a glycoside. Seeds are used traditionally to treat diabetes, asthma, aphrodisiac and to improve appetite. OBJECTIVE The present study was aime...
متن کاملcrocin enhanced functional recovery after sciatic nerve crush injury in rats
objective(s): crocin is a constituent of saffron and has many biological functions. the present study aimed to investigate the effects of intraperitoneal (ip) injection of crocin on sciatic nerve regeneration in male wistar rats. materials and methods: fifty-four rats were divided into 9 groups: groups 1-4 (intact + normal saline and intact + crocin at doses of 5, 20 and 80 mg/kg, respectively)...
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ژورنال
عنوان ژورنال: BMC Complementary Medicine and Therapies
سال: 2020
ISSN: 2662-7671
DOI: 10.1186/s12906-020-02950-3